{"id":29320,"date":"2026-07-08T08:02:14","date_gmt":"2026-07-08T08:02:14","guid":{"rendered":"https:\/\/neopharm.ge\/?post_type=product&#038;p=29320"},"modified":"2026-07-08T08:03:33","modified_gmt":"2026-07-08T08:03:33","slug":"%e1%83%9f%e1%83%9d%e1%83%a1%e1%83%a2%e1%83%94%e1%83%a0%e1%83%98%e1%83%9c%e1%83%98-%e2%84%9620-%e1%83%99%e1%83%90%e1%83%a4","status":"publish","type":"product","link":"https:\/\/neopharm.ge\/en\/product\/%e1%83%9f%e1%83%9d%e1%83%a1%e1%83%a2%e1%83%94%e1%83%a0%e1%83%98%e1%83%9c%e1%83%98-%e2%84%9620-%e1%83%99%e1%83%90%e1%83%a4\/","title":{"rendered":"Josterin No. 20 Capsules"},"content":{"rendered":"<p>Instructions for use<br \/>\nParapharmaceutical product<br \/>\n<strong>\u10df\u10dd\u10e1\u10e2\u10d4\u10e0\u10d8\u10dc\u10d8<\/strong><br \/>\nJOSTERIN<\/p>\n<p class=\"translation-block\"><strong>Pharmacological group:<\/strong> Laxative.<br> <strong>Dosage form:<\/strong> Capsules.<br>\nComposition: Crushed buckthorn fruits (Fructus Rhamni catharticae) \u2013 0.297 g; excipient: calcium stearate;<br>\nBuckthorn fruit powder contains anthraglycosides (4%), including frangulaemodin, chrysophanol (also known as glucofrangulin), rhamnoxatin (frangulin), and the bioside of frangula-emodin \u2013 josterin. The fruit powder also contains tannins, carbohydrates, organic acids, anthocyanins, resins, and flavonoids (quercetin, rhamnetin, kaempferol, rhamnocitrin).<br> <strong>Pharmacological action:<\/strong> \u201cZHOSTERIN\u201d has a laxative effect due to its content of anthraglycosides. These substances irritate intestinal interoreceptors and enhance peristalsis, acting on the large intestine and promoting its rapid evacuation.<br>\nThe laxative effect develops after 8\u201310 hours. The slow and predominantly large-intestine-specific action of the product is explained by the gradual breakdown of anthraglycosides in the intestine. The active substance accumulates in a sufficient amount to produce a laxative effect only when it reaches the large intestine.<br> <strong>Indications:<\/strong> Used as an adjunct in complex therapy. Used for atonic and spastic constipation. In addition to its primary action, it exhibits local anti-inflammatory, antispasmodic, demulcent, and bactericidal properties. Recommended for use in colitis, hemorrhoids, rectal ulcers, and fissures.<br> <strong>Contraindications:<\/strong><br>\n\u2022 Hypersensitivity to the components of the product;<br>\n\u2022 Hemorrhagic bleeding;<br>\n\u2022 Chronic cholecystitis.<br> <strong>Method of administration and dosage:<\/strong><br>\nTake 1 capsule once daily, before bedtime, every other day, regardless of meal timing.<br>\nThe duration of administration and dosing interval are determined individually.<br> <strong>Pediatric use:<\/strong> Not studied.<br>\nSide effects: Spastic abdominal pain, flatulence, nausea, vomiting, discoloration of urine, allergic reactions.<br> <strong>Precautions:<\/strong> The product should be administered with caution during pregnancy and lactation, in hepatic and\/or renal insufficiency, and during the postoperative period following surgery on the abdominal organs.<br> <strong>Pregnancy and lactation:<\/strong> Not studied.<br>\nEffect on the ability to drive vehicles and operate machinery: Does not affect the ability to drive vehicles or operate machinery.<br>\nInteraction with other medicinal products: Inhibits the absorption of tetracycline.<br> <strong>Packaging:<\/strong> 10 capsules per PVC\/Alu blister, 2 blisters in a cardboard box.<br> <strong>Storage:<\/strong> Store at room temperature, in a dry place protected from light.<br> <strong>Shelf life:<\/strong> 2 years;<br>\nThe product must not be used after the expiry date or if any defects are detected during visual inspection.<br> <strong>Dispensing conditions:<\/strong> Pharmaceutical product group III \u2013 available without a prescription.<br> <strong>Manufacturer:<\/strong> LLC \u201cNeopharm\u201d.<\/p>\n<p>Georgia. Tbilisi. D. Agmashenebeli Alley, 12th km;<br \/>\nTel\/Fax: + 995 (32) 259-64-46; 259-57-90;<\/p>","protected":false},"excerpt":{"rendered":"<p>\u10d2\u10d0\u10db\u10dd\u10e7\u10d4\u10dc\u10d4\u10d1\u10d8\u10e1 \u10d8\u10dc\u10e1\u10e2\u10e0\u10e3\u10e5\u10ea\u10d8\u10d0 \u10de\u10d0\u10e0\u10d0\u10e1\u10d0\u10db\u10d9\u10e3\u10e0\u10dc\u10d0\u10da\u10dd \u10e1\u10d0\u10e8\u10e3\u10d0\u10da\u10d4\u10d1\u10d0 \u10df\u10dd\u10e1\u10e2\u10d4\u10e0\u10d8\u10dc\u10d8 JOSTERIN \u10e4\u10d0\u10e0\u10db\u10d0\u10d9\u10dd\u10da\u10dd\u10d2\u10d8\u10e3\u10e0\u10d8 \u10ef\u10d2\u10e3\u10e4\u10d8:\u00a0\u10e1\u10d0\u10e4\u10d0\u10e6\u10d0\u10e0\u10d0\u10d7\u10dd \u10e1\u10d0\u10e8\u10e3\u10d0\u10da\u10d4\u10d1\u10d0. \u10ec\u10d0\u10db\u10da\u10d8\u10e1 \u10e4\u10dd\u10e0\u10db\u10d0:\u00a0\u10d9\u10d0\u10e4\u10e1\u10e3\u10da\u10d4\u10d1\u10d8. \u10e8\u10d4\u10db\u10d0\u10d3\u10d2\u10d4\u10dc\u10da\u10dd\u10d1\u10d0: \u10ee\u10d4\u10e8\u10d0\u10d5\u10d8\u10e1 \u10d3\u10d0\u10ec\u10d5\u10e0\u10d8\u10da\u10db\u10d0\u10dc\u10d4\u10d1\u10e3\u10da\u10d8 \u10dc\u10d0\u10e7\u10dd\u10e4\u10d4\u10d1\u10d8 (F\u10e0\u10e3\u10ea\u10e2\u10e3\u10e1 \u10e6\u10f0\u10d0\u10db\u10dc\u10d8 \u10ea\u10d0\u10e2\u10f0\u10d0\u10e0\u10e2\u10d8\u10ea\u10d0\u10d4) \u2013 0,297\u10d2;<\/p>","protected":false},"featured_media":29321,"comment_status":"open","ping_status":"closed","template":"","meta":[],"product_brand":[],"product_cat":[77,76],"product_tag":[],"class_list":["post-29320","product","type-product","status-publish","has-post-thumbnail","product_cat-77","product_cat-76","first","instock","shipping-taxable","purchasable","product-type-simple"],"_links":{"self":[{"href":"https:\/\/neopharm.ge\/en\/wp-json\/wp\/v2\/product\/29320","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/neopharm.ge\/en\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/neopharm.ge\/en\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/neopharm.ge\/en\/wp-json\/wp\/v2\/comments?post=29320"}],"version-history":[{"count":0,"href":"https:\/\/neopharm.ge\/en\/wp-json\/wp\/v2\/product\/29320\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/neopharm.ge\/en\/wp-json\/wp\/v2\/media\/29321"}],"wp:attachment":[{"href":"https:\/\/neopharm.ge\/en\/wp-json\/wp\/v2\/media?parent=29320"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/neopharm.ge\/en\/wp-json\/wp\/v2\/product_brand?post=29320"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/neopharm.ge\/en\/wp-json\/wp\/v2\/product_cat?post=29320"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/neopharm.ge\/en\/wp-json\/wp\/v2\/product_tag?post=29320"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}