ალოფერის სიროფი
SIRUPUS ALOFERI
Instructions for use
Dosage form: Syrup.
Composition:
Ferrous sulfate – 0.962 g, equivalent to iron content;
Diluted hydrochloric acid – 1.95 g;
Ascorbic acid – 0.52 g;
Aloe juice syrup – up to 130 g;
(1 mL of syrup contains 9.62 mg of iron);
Aloe juice contains a complex of biologically active substances: anthracene derivatives (aloe-emodin, aloin, aloinoside), bitter glycosides, vitamins, enzymes, organic acids, polysaccharides.
Pharmacological action:
Ferrous sulfate:
· Iron is a structural component of heme;
· It is necessary for hemoglobin synthesis;
· It is a component of myoglobin and a number of enzymes;
· It is deposited in the body.
Ascorbic acid:
· Promotes the reduction of trivalent iron to divalent ionic iron;
· Improves the absorption of iron from food;
· Regulates capillary permeability;
· Ensures the synthesis of collagen and procollagen;
· Plays an important role in redox processes;
Aloe juice syrup:
· Has bactericidal, antiviral, and anti-inflammatory effects;
· Contains biogenic stimulants;
· Enhances the body's resistance to infectious diseases;
· Enhances regenerative processes of the skin and mucous membranes;
Hydrochloric acid:
· Improves the absorption of iron from the gastrointestinal tract.
Indications: Used as an adjunct in complex therapy.
· Iron-deficiency (hypochromic) anemias of various etiologies;
· Increased iron requirements (prepubertal and pubertal age, lactation period);
· Alimentary deficiency of iron and vitamins.
Contraindications:
· Anemias of other etiologies;
· Hemosiderosis, hemochromatosis;
· Crohn's disease, ulcerative enterocolitis;
· Liver cirrhosis, chronic pancreatitis;
· Diffuse glomerulonephritis;
· Pregnancy.
· Diabetes mellitus.
Side effects:
Anorexia, nausea, diarrhea, tachycardia, skin rash. Blood pressure should be monitored during treatment. If any side effects not mentioned in the instructions for use occur, the patient should consult the treating physician or pharmacist.
Method of administration and dosage:
Orally.
Adults and children over 14 years of age: 1–2 teaspoons of syrup diluted in 50 mL of water 3 times daily after meals. Children under 3 years of age: the dosage of the medicinal product is determined individually, taking body weight into account. See table;
Daily doses of Alofer syrup according to the child's body weight:
| Child's weight in kg | 3-4კგ | 5-6კგ | 7-8კგ | 9-10კგ | 11-12კგ | 13-14კგ | 15-16კგ |
| Daily dose in ml | 0,5-0,6მლ | 0,7-0,9მლ | 1,0-1,2მლ | 1,3-1,7მლ | 1,8-2,0მლ | 2,1-2,2მლ | 2,3-2,5მლ |
| Daily dose in drops | 15-18წვთ | 21-27წვთ | 30-36წვთ | 39-51წვთ | 54-60წვთ | 63-66წვთ | 69-75წვთ |
The syrup dose is divided into 2–3 administrations.
Children aged 3 to 6 years: half a teaspoon of syrup diluted in 30 mL of water 2–3 times daily after meals;
Children aged 6 to 14 years: 1 teaspoon of syrup diluted in 30 mL of water 2–3 times daily after meals;
The duration of the treatment course is 8–12 weeks.
Shake the bottle well before use!
After taking the medicinal product, it is recommended to drink up to 200 mL of water.
Missed dose: If a dose is missed, a double dose must not be taken. The subsequent dose should be taken according to the original schedule.
Pregnancy and lactation: When iron deficiency is confirmed in the body, Alofer syrup is prescribed during pregnancy and lactation.
Interaction with other medicinal products or other forms of interaction: Concomitant use with thiazide diuretics, licorice preparations, and corticosteroids increases the risk of developing potassium deficiency.
Concomitant administration with tetracycline antibiotics, penicillamines, and antacid medicinal products should be avoided, as iron absorption is reduced.
Effect on drivers and personnel working with potentially hazardous machinery: Taking the medicinal product does not affect concentration or the ability to operate machinery.
Special instructions: After taking the medicinal product, it is recommended to drink up to 200 mL of water.
Precautions: Prolonged use of the medicinal product may cause potassium depletion and enhance the effects of cardiac glycosides and antiarrhythmic medicinal products.
Overdose: Symptoms of overdose include weakness, fatigue, paresthesia, pallor, decreased blood pressure, abdominal pain, confusion, diarrhea with blood, vomiting, and cyanosis.
Treatment: Gastric lavage; administration of milk and raw eggs. For specific treatment, deferoxamine is administered orally and parenterally. In acute poisoning, when iron has not yet been adsorbed from the gastrointestinal tract, 5–10 g of deferoxamine is administered (the contents of 10–20 ampoules are dissolved in water). To bind absorbed iron, deferoxamine is administered slowly intramuscularly: in children – 15 mg/hour; in adults – 5 mg/kg/hour (up to 80 mg/kg/day). In mild poisoning, 1 g is administered intramuscularly every 4–6 hours in children; in adolescents – 50 mg/kg (up to 4 g/day).
Presentation:
Primary packaging: 130 g of syrup in a dark-colored glass or polymer bottle. Secondary packaging: the bottle is placed in a cardboard box together with the instructions for use.
Shelf life: 2 years.
Storage: Store at 18–25˚C, protected from light.
Do not use the medicinal product after the expiry date.
Dispensing conditions: Pharmaceutical product Group III – available without a prescription.
Manufacturer: LLC “Neopharm”.
Georgia. Tbilisi. D. Agmashenebeli Alley, 12th km;
ტელ/ფაქსი: + 995 (032) 259-64-46; 259-57-90;
MAECENAS IACULIS
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