Pelvidol 20 Tablets

It is a dietary supplement containing palmitoylethanolamide (PEA) and magnesium. It is used as an adjunct to meet an increased demand for PEA and magnesium in gynecological and urological clinical practice—specifically in cases of painful, inflammatory, and spastic conditions affecting the male and female reproductive systems.

Taking the product helps replenish endogenous stores of palmitoylethanolamide, which are depleted in conditions associated with peripheral nerve pain and caused by mast cell hyperactivity.

Magnesium contributes to the maintenance of electrolyte balance, participates in cell division processes, reduces fatigue, and plays an important role in energy metabolism. It also affects psychological, joint, nervous, and muscular systems. Notably, acting as a calcium antagonist, it exerts a relaxing effect on uterine muscles.

მაგნიუმი უწყობს ხელს ელექტროლიტური ბალანსის შენარჩუნებას, მონაწილეობს უჯრედების დაყოფის პროცესებში, ამცირებს დაღლილობას და ენერგეტიკულ მეტაბოლიზმში მნიშვნელოვან როლს ასრულებს. ის ასევე მოქმედებს ფსიქოლოგიურ, სახსაროვან, ნერვულ და კუნთოვან სისტემებზე. განსაკუთრებით კი, როგორც კალციუმის ანტაგონისტი, იძლევა საშვილოსნოს კუნთების დექონტრაქტურ ეფექტს.

Gynecology

Chronic pelvic pain, associated with various pathologies of the pelvic region (endometriosis, interstitial cystitis, recurrent cystitis, chronic prostatitis, irritable bowel syndrome, etc.), constitutes a nosological entity with a dual localization—at the tissue level and at the level of the spinal cord.

Tissue localization is associated with increased sensitivity of the terminals of peripheral sensory nerves that innervate various organs within the pelvic cavity, leading to diffuse inflammatory pain and associated stress.

At the level of the spinal cord, a chronic neuroinflammatory process leads to central sensitization, which intensifies neuropathic pain and increases the intensity of the patient's pain.

Urology

Functional disorders of the prostate—particularly within the neural and fibromuscular tissue—are frequently encountered in urological pathologies (benign prostatic hyperplasia and chronic prostatitis).

In these conditions, neuroinflammation—caused by dysregulation and localized oxidative stress—is dominant..

Mast cell hyperactivity leads to peripheral sensitization (pelvic pain) and vascular-edematous phenomena. Meanwhile, the chronic neuroinflammatory process affects the reactivity of spinal microglia, resulting in an intensification of pain (central sensitization).

Ophthalmology

Palmitoylethanolamide (PEA), which occurs naturally in the human body and in many food products, plays an important modulatory role in controlling mast cell hypergranulation within the innervated structures of the eye—a process linked to neuronal damage.

This function provides neuroprotection and prevents the development of neurodegenerative conditions, such as:

• Increased intraocular pressure
• Glaucoma
• Diabetic retinopathy
• Metabolic or dysmetabolic optic neuropathy
• Pain after refractive surgery
• Trigeminal neuralgia
• In these cases, the administration of palmitoylethanolamide is beneficial, as its endogenous production decreases during inflammatory conditions.

Instructions for Use

It is recommended to take 1 tablet twice a day with a sufficient amount of water.

Warning

• Keep out of reach of children (children under 3 years of age).
• Do not exceed the recommended dose..
• The supplement is not a substitute for a balanced and varied diet..
• It is advisable to consult a doctor before use..
• Store in a cool, dry place, away from heat sources.
• The shelf life applies to an unopened, properly stored product.